11 DESCRIPTION
You should share an up-to-date medication list with your prescriber and pharmacist. This can help them check for potential interactions. Taking too much vardenafil may raise your risk of side effects, such as headache or back pain. Some people have reported temporary vision problems after taking more vardenafil than recommended. But certain side effects could become dangerous, such as low blood pressure which could cause you to feel dizzy or faint.
2.4 Concomitant Medications
You should only take one dose per day. Your vardenafil dosage may be lower if you have liver problems or are 65 years or older. You may also need a lower dosage if you take certain medications that interact with vardenafil. With GoodRx, you can save over 80% off the average retail price at certain pharmacies. Vardenafil is an oral medication prescribed to treat erectile dysfunction (ED).
What are some things I need to know or do while I take this drug?
In fact, it’s a first-choice treatment for ED. Vardenafil is an “as-needed” medication that can start working within 15 minutes to 1 hour. So you should take your doses shortly before you plan to have sex. In this guide, we’ll discuss more details about typical vardenafil dosages. This includes the recommended starting dose and when adjustments may be needed. If you’ve taken too much vardenafil, contact your prescriber for guidance. You can also call Poison Control at 1-800-222-1222. But if anything seems severe or life threatening, call 911 or go to the nearest ER. There are ways to save on vardenafil, which is only available as a generic medication. GoodRx can help you save over 80% off the average retail price of the generic version. The price for five of the 10 mg vardenafil tablets at certain pharmacies is as low as $25.04 with a free GoodRx discount. The typical starting vardenafil dosage for erectile dysfunction is 10 mg by mouth about 1 hour before sex. If needed, your dosage can be raised up to a maximum of 20 mg per day. You should only take vardenafil once a day, regardless of what dose you’ve been prescribed.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Levitra Soft Tabs | 20mg | 10 Pills | 52.27€ 49.78€ | |
| Levitra Soft Tabs | 20mg | 60 + 4 Pills | 178.40€ 169.90€ | |
| Kamagra Polo | 100 mg | 32 Pills | 125.88€ 119.89€ | |
| Viagra Original | 100mg | 12 Pills | 72.54€ 69.09€ | |
| Kamagra Soft Tabs | 100 mg | 272 + 12 Pills | 593.42€ 565.16€ | |
| Viagra Generic | 150mg | 360 + 10 Pills | 423.48€ 403.31€ | |
| Cialis Generic | 40mg | 90 + 6 Pills | 171.35€ 163.19€ | |
| Cialis Generic | 2.5mg | 30 + 4 Pills | 51.95€ 49.48€ | |
| Kamagra 100 mg | 100 mg | 360 + 6 Pills | 839.95€ 799.95€ | |
| Kamagra Gold | 50 mg | 84 + 6 Pills | 224.77€ 214.07€ |
Adults ages 65 and older may need to take a lower vardenafil dosage to reduce the risk of side effects. The same can be said for people with liver disease or if you take certain interacting medications.
Clinical Information
It is not known if or how vardenafil could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant. People who can breastfeed are not usually prescribed vardenafil. It is not known if vardenafil passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed.
Tretinoin (PG-free) Solution
Grapefruit or grapefruit juice can raise vardenafil levels in your body, which can increase the risk of side effects. Vardenafil orally disintegrating tablets should not be taken with water or liquids. Let it dissolve on your tongue without crushing it. There are no known interactions between vardenafil and alcohol. Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. Your prescriber can help you figure out the best vardenafil dosage for you. Vardenafil, sold under the brand name Levitra among others, is a medication that is used for treating erectile dysfunction. Vardenafil's indications and contraindications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil.
- Vardenafil can cause temporary vision disturbances.
- Do not use if you have a recent history of heart attack.
- It should be used with caution in those with kidney issues.
- Men with liver problems should seek medical advice.
Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's.
13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility
You shouldn’t try to adjust your dosage on your own. Adults ages 65 and older tend to have higher amounts of vardenafil in their bloodstream after a dose than younger adults (even if they take the same dose). This means older adults may have a greater risk or be more sensitive to side effects. If you’re 65 or older, it’s recommended to lower the starting vardenafil dosage to 5 mg and slowly raise it if needed. The kidneys help clear vardenafil from the body.
J. Chromatogr. B
If your kidneys aren’t working as expected, vardenafil can build up and cause side effects. If you have mild to moderate kidney disease, you’ll likely take the standard vardenafil dosage as discussed above. But if you have severe kidney disease, your prescriber may suggest an alternative to vardenafil. It’s also recommended that people receiving dialysis avoid this medication. Vardenafil hasn’t been well studied for safety or effectiveness in this population. Despite the structural differences between vardenafil and sildenafil, they both show similar ocular side effects due to their similar selectivity overlap with PDE6, an enzyme found in the eye. Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from penetration to ejaculation. The common, adverse drug reactions (side effects) are the same as with other PDE5 inhibitors. The frequent vardenafil-specific side-effect is nausea; the infrequent side effects are abdominal pain, back pain, photosensitivity, abnormal vision, eye pain, facial edema, hypotension, palpitation, tachycardia, arthralgia, myalgia, rash, itch, and priapism. One possibly serious, but rare, side effect with vardenafil is heart attack. Also, in rare cases, vardenafil use may cause priapism, a very painful emergency condition that can cause impotence if left untreated. In October 2007, the U.S. Food and Drug Administration (FDA) announced that a warning about possible deafness (sudden hearing loss) would be added to the drug labels of vardenafil, and other PDE5 inhibitors.
Related Products
Your liver helps metabolize (break down) vardenafil. Similar to the kidneys, if your liver isn’t working well, vardenafil can build up. The recommended vardenafil dosages for liver disease depend on how severe the condition is: Mild liver disease: Follow the typical vardenafil dosages as described above. Mild liver disease: Follow the typical vardenafil dosages as described above. Moderate liver disease: The starting dosage is 5 mg about 1 hour before sex. Vardenafil should not be used by people taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension (low blood pressure). Further, vardenafil causes lengthening of the QT interval. Therefore, it should not be taken by people taking other medications that affect the QT interval (such as amiodarone).
- Vardenafil is part of phosphodiesterase inhibitors.
- It may interact with certain blood pressure medications.
- The drug is usually effective within 30 minutes.
- Store vardenafil in a cool, dry place away from children.
Vardenafil was co-marketed by Bayer Pharmaceuticals, GlaxoSmithKline, and Schering-Plough under the brand name Levitra.
- Unlike some ED medications, vardenafil may work in the presence of fatty foods.
- It requires sexual stimulation to produce an effect.
- Alcohol can increase the risk of side effects.
- Avoid combining with recreational drugs.
As of 2005, the co-promotion rights of GSK on Levitra have been returned to Bayer in many markets outside the US. Thus, because of European Union trade rules, parallel imports might result in Vivanza sold next to Levitra in the EU. An orally disintegrating form, marketed as Staxyn and Levitra Soft, has been gaining approvals in countries such as the United States[11] and Canada. The US Food and Drug Administration (FDA) has found vardenafil and other synthetic PDE5 inhibitors in numerous products marketed as "herbal" supplements or "all natural" products for male enhancement.
| Side Effect | Frequency | Severity | Recommended Action |
|---|---|---|---|
| Headache | Common | Mild | Take analgesics, hydration |
| Flushing | Common | Mild | Cool environment, hydrate |
| Nasal Congestion | Moderate | Mild | Use decongestants if needed |
| Dizziness | Less common | Mild | Sit or lie down immediately |
| Muscle Pain | Rare | Mild | Consult doctor if persists |
^ a b c d "Levitra (vardenafil hydrochloride) tablets, for oral use Initial U.S. Approval: 2003". ^ "Levitra (Vardenafil) is A Drug Used to Treat Erectile Problems in Men" (in German).
5.10 Combination with Other Erectile Dysfunction Therapies
This can be raised to a maximum of 10 mg. Severe liver ed medications disease: It’s not recommended to take vardenafil if you have severe liver disease. In many cases, lowering your vardenafil dosage can help manage these interactions. Vardenafil’s labeling gives specific dosage adjustments for certain interactions, as detailed in the table below. This is not a complete list of vardenafil interactions. "Potency, selectivity, and consequences of nonselectivity of PDE inhibition". "Effects of vardenafil administration on intravaginal ejaculatory latency time in men with lifelong premature ejaculation".
7.2 Effect of Other Drugs on Vardenafil
In particular, make sure that you discuss if you are using any of the following before taking vardenafil. Tell your healthcare provider about all medicines that you take or have recently taken. This may not be a complete list of medicines that can interact with vardenafil. If you or someone else has taken too much vardenafil, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222. Take it as your healthcare provider recommends, which is usually about one hour before planned sexual activity.
What do I need to tell my doctor BEFORE I take this drug?
Do not take double or extra doses. This survey is being conducted by the WebMD marketing sciences department. Vardenafil is a first-choice treatment for erectile dysfunction. You should take it as needed shortly before having sex. The typical vardenafil dosage ranges from 5 mg to 20 mg, taken about 1 hour before sex. "Counseling Patients About Sexual Issues: Drug-Induced Priapism". ^ "FDA Announces Revisions to Labels for Cialis, Levitra and Viagra".
Do erectile dysfunction medicines increase sexual desire?
The typical starting vardenafil dosage is 10 mg by mouth about 1 hour before sexual activity. Depending on how effective it is and whether you have side effects, your prescriber may adjust this dose to anywhere between 5 mg and 20 mg (the maximum dose). Don’t take vardenafil more than once a day, regardless of which dose you’ve been prescribed. Vardenafil comes as both a traditional tablet and an orally disintegrating tablet (ODT). If you’re taking the ODT, place the tablet on your tongue.
How should I store vardenafil?
You shouldn’t drink water while the tablet is dissolving. Depending on your age and medical history, you may need to take a lower vardenafil dosage. This is also true if you take certain medications that interact with vardenafil. These dosage adjustments help to lower the risk of side effects from vardenafil. Your prescriber will be in charge of determining whether you should take a different vardenafil dosage.