Cost Comparison of Popular Erectile Dysfunction Creams

Causes of ED range from temporary, manageable triggers to more serious, chronic health conditions. If ED is a chronic issue for you (or even if it’s an occasional problem), it’s worth looking into possible treatments. Untreated erectile dysfunction can lead to self-esteem issues and relationship strain.

Understanding Erectile Dysfunction

You develop scarring or hard areas on your penis. The alprostadil solution looks cloudy, is a different color or has debris. Go to the nearest emergency room if your erection lasts longer than four hours. No, you shouldn’t combine alprostadil with other oral medications for ED. Taking alprostadil in combination with Viagra or other similar drugs may increase toxic effects.

Availability Through Trusted Providers

The most common complication includes a prolonged erection that lasts longer than four hours. Without proper treatment, it can cause permanent damage to your penile tissue. The average cost of alprostadil is over $500 for a 5-milliliter (teaspoon size) vial. The cost per dose depends on how much you need to inject, which varies from person to person. The lower the volume that you need to inject, the more doses per vial you’ll get, which makes it cheaper per dose. So ED treatments aren’t just about sexual performance — they can improve your overall quality of life. If a medical professional thinks PDE5 inhibitors (phosphodiesterase type 5 inhibitors) — like Viagra, tadalafil (Cialis), vardenafil (Levitra®), and avanafil (Stendra®) — won’t work for you, they may suggest other treatments for erectile dysfunction.

Product	Dosage	Quantity + Bonus	Price
Kamagra Gold	50 mg	360 + 6 Pills	713.95€ 679.95€	Buy
Kamagra Polo	100mg	12 Pills	60.21€ 57.34€	Buy
Cialis Black	80mg	30 + 2 Pills	89.11€ 84.87€	Buy
Viagra Professional	100mg	120 + 4 Pills	262.83€ 250.31€	Buy
Kamagra Polo	100mg	60 + 4 Pills	189.39€ 180.37€	Buy
Cialis Generic	20mg	120 + 8 Pills	188.15€ 179.19€	Buy
Super Kamagra	160 mg	20 + 4 Pills	155.35€ 147.95€	Buy
Levitra Original	20mg	76 + 4 Pills	344.39€ 327.99€	Buy
Viagra Super Active	100mg	90 + 10 Pills	165.61€ 157.72€	Buy
Viagra Soft Tabs	100mg	30 + 4 Pills	83.06€ 79.10€	Buy
Cialis Super Active	20mg	90 + 10 Pills	314.14€ 299.18€	Buy
Cialis Original	20mg	64 + 4 Pills	274.18€ 261.12€	Buy

There are a few types of erectile dysfunction creams and gels on the market these days, each with a different mechanism. Mostly, though, ED creams and gels work by improving blood flow to the penis, allowing you to get an erection during sexual activity or stimulation.

What Are Topical Creams for Erectile Dysfunction?

Get answers to common questions about ED and learn about your treatment options. Be ready for sex whenever you're in the mood If you’re tired of swallowing pills or dealing with the side effects of oral erectile dysfunction (ED) medications, there may be another solution that’s simpler and more direct. Topical erectile dysfunction creams and gels are gaining traction as a new way to combat ED. Are these creams and gels really comparable alternatives to established medications like sildenafil (Viagra®) and tadalafil (Cialis®)? If so, what is the best cream for erectile dysfunction?

MED3000 (Eroxon)

We’ll take a look at how these products work, their benefits, erectile cream side effects, and what else you need to know before trying them. We’ll also cover other proven ED treatments and lifestyle changes that may improve your sexual health. Erectile dysfunction is a common type of sexual dysfunction affecting roughly 30 million men in the United States. Those with ED find it difficult to get and maintain an erection firm enough for sexual intercourse. Many guys struggle to get an erection from time to time. Not all erection creams and gels are made equally.

• Scientific research on topical ED creams continues to evolve.
• They are sometimes marketed as "herbal" or "natural" but verification is needed.
• The choice of cream depends on individual health, preference, and doctor advice.
• Proper application technique can maximize blood flow enhancement.
• Regular use may require monitoring for skin reactions.

Some have a fair amount of science-backed proof, while others have hardly been studied at all.

User Demographic	Preferred Cream Type	Satisfaction Level	Reasons for Preference	Comments
Age 30-40	Natural ingredients	4.5/5	Fewer side effects	"Works well with minimal irritation"
Age 50-60	Fast-acting gels	4.2/5	Quick onset, discreet application	"Easy to use before intimacy"
Age 20-30	Herbal-based creams	4.3/5	Natural approach, safety concern	"Trusted natural ingredients"
General audience	Multi-ingredient formulas	4.0/5	Broader efficacy	"Love that it enhances confidence"

So, what is the best erection cream or gel?

Brand Name	Main Active Ingredient	Price Range	User Ratings	Availability
ErecCream Plus	L-arginine	$20-$40	4.5/5	Online, pharmacies
VigorGel	Yohimbine	$15-$35	4.2/5	Online only
LibidoBoost	Maca Extract	$10-$25	4.0/5	Stores, online
VitalErect	Ginseng Extract	$25-$50	4.3/5	Pharmacies
PassionGel	DHEA	$30-$60	4.1/5	Special order

We’ll go over a few options below.

Erectile Dysfunction Cream

Each patient received 16 applications, eight of the active cream and eight placebo. The creams were applied alternatively on successive occasions and the results recorded. Results: The active cream, applied on 77 occasions, resulted in three good and 13 partial erections. The placebo cream, applied on 76 occasions, yielded four good and 13 partial erections. Conclusions: We were unable to reproduce the successful results reported by others; in the present study the active cream performed no better than placebo.

Alprostadil Cream

Reviewed by Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing Men will soon have a new option for treating erectile dysfunction (ED) that supposedly works faster than regular ED medication — and is available without a prescription. In June, the FDA approved the over-the-counter sale of MED3000 (Eroxon), a topical gel treatment for ED. MED3000 is pills for men supplied in single-use tubes. The contents are rubbed onto the head of the penis immediately before sexual intercourse. The U.S. Food and Drug Administration (FDA) has authorized just one topical ED treatment: Eroxon®. This new-to-market erection gel got the FDA’s go-ahead in 2023, making it one of the only non-prescription erectile dysfunction treatments available in the U.S.

• Topical creams offer a non-invasive approach compared to injections or surgery.
• They can be used on demand or as part of a scheduled treatment plan.
• Compatibility with condoms and lubricants should be verified to avoid degradation.
• Some creams may need to be applied 15-30 minutes before intimacy.
• Monitoring for side effects ensures safe and effective treatment.

Though some news outlets are calling Eroxon “topical Viagra” and “Viagra cream,” these are misnomers.

Conclusion: Make the Change That Matters Most

The gel contains a combination of volatile solvents which, when applied to the head of the penis, evaporate rapidly, stimulating nerve endings through an initial cooling effect, followed by a warming sensation. This reaction releases nitric oxide, relaxing the smooth muscle tissue inside the penis and increasing blood flow that is needed to obtain an erection. Clinical trials found that 65% of men who used MED3000 achieved an erection within 10 minutes and maintained it long enough to have sex. Common prescription ED drugs like tadalafil (Cialis) and sildenafil (Viagra) take around 30 minutes to work. The common side effects of MED3000 were headaches and nausea, but these occurred in only 1% to 3% of men.

FDA Warnings

No side effects were reported among sexual partners. U.S. prices are not yet available, but in the United Kingdom, where Eroxon is already available over-the-counter, the cost is equivalent to about $32 (U.S.) for a four-pack. Matthew Solan, Former Executive Editor, Harvard Men's Health Watch Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Eroxon doesn’t actually contain sildenafil — or any medication, for that matter.

LinkOut - more resources

The cost of alprostadil may also depend on: The pharmacy where you pick up your prescription. Alprostadil can help treat erectile dysfunction and improve your sex life. ED can cause a lot of different feelings — frustration, embarrassment, shame and even humiliation. You may even experience these feelings when you seek help from a healthcare provider. But ED is common, and providers are available to help you and make you as comfortable as possible with your questions and concerns.

Key Ingredients in ED Creams

Ask a provider if alprostadil is the best treatment for you or if another medication is better. Sign up for our Health Essentials emails for expert guidance on nutrition, fitness, sleep, skin care and more. Learn more about the Health Library and our editorial process. Cleveland Clinic’s health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date clinical standards. Alprostadil (Injectable and Transurethral) ( Updated 8/3/2021. According to the brand’s website, the topical gel works by cooling and warming the penis, stimulating the nerves.

Other ED Treatments

Treasure Island, FL: StatPearls Publishing; 2023 Jan-. At Cleveland Clinic, we offer specialty care that’s focused on you. We understand that patients often have questions about any new treatments they take. This FAQ is meant to supplement your advice and recommendation, providing further clinical information on the efficacy and safety of Eroxon®. Eroxon® is the first and only FDA-cleared, topical, OTC product to help treat erectile dysfunction (ED).

Consulting a Healthcare Professional

It’s fast-acting and offers a safe treatment option for both patients and their partners. Below, we’ve provided clear, comprehensive information about how Eroxon® works, its benefits, and how it should be used. Objective: To repeat a previous study on the use of a topical treatment for erectile failure using a vasoactive cream. Patients and methods: Fourteen patients with erectile failure who had previously responded to intracorporeal injection therapy were enrolled in a randomized placebo-controlled trial. They were given two topical applications, comprising either a cream containing aminophylline, isosorbide dinitrate and co-dergocrine mesylate, or a placebo cream of similar appearance containing no pharmacologically active ingredients. This might increase blood flow, giving your erection a boost.

• Use of ED creams is not recommended in case of penile infections or dermatological issues.
• Ensure accurate dosing to avoid priapism, a prolonged erection.
• Topical ED therapies are especially useful for men with contraindications to oral meds.
• Careful storage and handling optimize the product’s shelf life.
• Combining therapies under medical supervision can yield better outcomes.

The product leaflet notes that you may need to try Eroxon a few times before it works — although most men experience an erection the first or second time they apply it. The insert also warns that Eroxon is compatible with latex condoms only, so keep that in mind! One well-known topical ED treatment is alprostadil cream, also known by the brand name Vitaros®. Alprostadil is a type of prostaglandin (a natural vasodilator), meaning it helps blood vessels relax. This topical ED cream works by stimulating blood flow, making it easier to get (and maintain) an erection.

Other Topical Agents: Papaverine, Verapamil, and More

Please note the date of last review or update on all articles. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. Eroxon® is a fast-acting treatment gel for erectile dysfunction (ED) that can be applied immediately before sexual activity and is clinically proven to help you get an erection within 10 minutes. As the first-and-only ED gel, Eroxon® offers men and their partners results without the side effects of oral medicines or the inconvenience of getting a prescription. Clinically proven to work within 10 minutes† No one should be forced to plan ahead to enjoy intimate moments, women libido pills and today’s treatments make it difficult to connect spontaneously.

Key Takeaways

Now, men and their partners have a fast-acting treatment option for ED: Eroxon® gel. Learn how Eroxon®’s easy-to-apply gel helps men and their partners move seamlessly from date night to pillow talk. ...leading to increased blood flow in the penis to help achieve and maintain an erection. In clinical trials, Eroxon® helped men with ED achieve an erection within 10 minutes. * While it may not work for everyone, studies showed success in over 60% of men.